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Article

J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution.

Journal of bacteriology - 1 Mar 2012

Duncan Stacy S, Valk Pieter L, Shaffer Carrie L, Bordenstein Seth R, Cover Timothy L

Abstract excerpt

Chronic infection with Helicobacter pylori strains expressing the bacterial oncoprotein CagA confers an increased risk of gastric cancer. While much is known about the ancestry and molecular evolution of Western, East Asian, and Amerindian cagA sequences, relatively little is understood about a fourth group, known as "J-Western," which has been detected mainly in strains from Okinawa, Japan. We show here that...

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Identifiers

PMID: 22247512
DOI: 10.1128/JB.06340-11
PMCID: PMC3294863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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