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Article

Helicobacter pylori geographic variation: a window into global differences in gastric cancer incidence.

Microbiology and molecular biology reviews : MMBR - 24 Sept 2026

Okoye Chiamaka D, Caso Georgia C, Cover Timothy L

Abstract excerpt

SUMMARYHelicobacter pylori infection is the strongest known risk factor for gastric cancer, a leading cause of cancer-related deaths worldwide. There is marked global geographic variation in both the incidence of gastric cancer and genetic features of H. pylori strains. Geographic diversity among H. pylori strains can be linked to ancestral human migrations and subsequent H. pylori evolution within human...

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Identifiers

PMID: 42505113
DOI: 10.1128/mmbr.00204-24
PMCID: PMC13602960

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