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Article

An ancient ecospecies of Helicobacter pylori.

Nature - 1 Nov 2024

Tourrette Elise, Torres Roberto C, Svensson Sarah L, Matsumoto Takashi, Miftahussurur Muhammad, Fauzia Kartika Afrida, Alfaray Ricky Indra, Vilaichone Ratha-Korn, Tuan Vo Phuoc, Wang Difei, Yadegar Abbas, Olsson Lisa M, Zhou Zhemin, Yamaoka Yoshio, Thorell Kaisa, Falush Daniel

Abstract excerpt

Helicobacter pylori disturbs the stomach lining during long-term colonization of its human host, with sequelae including ulcers and gastric cancer1,2. Numerous H. pylori virulence factors have been identified, showing extensive geographic variation1. Here we identify a 'Hardy' ecospecies of H. pylori that shares the ancestry of 'Ubiquitous' H. pylori from the same region in most of the genome but has nearly fixed...

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Identifiers

PMID: 39415013
DOI: 10.1038/s41586-024-07991-z
PMCID: PMC11541087

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