Article
Rapid evolution of distinct Helicobacter pylori subpopulations in the Americas.
PLoS genetics - 1 Feb 2017
Thorell Kaisa, Yahara Koji, Berthenet Elvire, Lawson Daniel J, Mikhail Jane, Kato Ikuko, Mendez Alfonso, Rizzato Cosmeri, Bravo María Mercedes, Suzuki Rumiko, Yamaoka Yoshio, Torres Javier, Sheppard Samuel K, Falush Daniel
Abstract excerpt
For the last 500 years, the Americas have been a melting pot both for genetically diverse humans and for the pathogenic and commensal organisms associated with them. One such organism is the stomach-dwelling bacterium Helicobacter pylori, which is highly prevalent in Latin America where it is a major current public health challenge because of its strong association with gastric cancer. By analyzing the genome...
Topics
- Alleles
- DNA, Mitochondrial
- Evolution, Molecular
- Genome, Bacterial
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Indians, North American
- Latin America
- Phylogeny
