Article
Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes.
PloS one - 1 Jan 2013
Duncan Stacy S, Valk Pieter L, McClain Mark S, Shaffer Carrie L, Metcalf Jason A, Bordenstein Seth R, Cover Timothy L
Abstract excerpt
Helicobacter pylori infection is a risk factor for the development of gastric adenocarcinoma, a disease that has a high incidence in East Asia. Genes that are highly divergent in East Asian H. pylori strains compared to non-Asian strains are predicted to encode proteins that differ in functional...
Topics
- Alleles
- Bacterial Proteins
- Bacterial Typing Techniques
- DNA, Bacterial
- Evolution, Molecular
- Asia, Eastern
- Genes, Bacterial
- Genetic Markers
- Genetic Variation
- Genomics
- Helicobacter pylori
- Multilocus Sequence Typing
- Phylogeny
- Selection, Genetic
- Species Specificity