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Article

Isolation, expansion and characterisation of alloreactive human Th17 and Th1 cells.

Immunology letters - 30 Mar 2012

Ko K Kerry, Powell Maree S, Orlowski Eva, Prickett Sara, Krumbiegel Doreen, Hogarth P Mark

Abstract excerpt

Interleukin 17 producing T helper cells (Th17) and IFNγ producing Th1 cells are distinct subsets of effector memory CD4(+) T cells that are crucial to host immunity and have been linked to the pathology of certain inflammatory autoimmune diseases. We have developed a method for the isolation and long term culture of human Th17 and Th1 cells. Using allogeneic stimulation we have cultured homogeneous populations of...

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Source

Identifiers

PMID: 22245119
DOI: 10.1016/j.imlet.2011.12.007

Genes

CCR4
CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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