Article
Cutting edge: Phenotypic characterization and differentiation of human CD8+ T cells producing IL-17.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2009
Kondo Takaaki, Takata Hiroshi, Matsuki Fumichika, Takiguchi Masafumi
Abstract excerpt
Although IL-17-producing CD8(+) T cells (Tc17 cells) have recently been identified, the detailed information about these cells still remains unclear. In this article we describe a study investigating the phenotype and differentiation of human Tc17 cells. Human Tc17 cells were detected in a minor population of CD8(+) T cells and were predominantly found in CD27(-/+)CD28(+)CD45RA(-) memory subsets. They also...
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