Article

Phenotypic, molecular and functional characterisation of human <i>in vitro</i> -generated IL-17A+ CD8+ T-cells

2022-11-16

Abstract excerpt

IL-17A+ CD8+ T-cells, often referred to as Tc17 cells, have been identified at sites of inflammation in several immune-mediated inflammatory diseases including psoriasis and spondyloarthritis. Whilst much of our understanding of IL-17A+ CD8+ T-cells has been discerned from murine studies, human IL-17A+ CD8+ T-cells remain less-well characterised. We optimised an in vitro polarisation protocol to expand human IL-1...

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Literature Corpus work: 74d99653-e36a-5f4f-acf6-bed92eadecdf
DOI: 10.1101/2022.11.14.516164

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