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Article

Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2007

Sato Wakiro, Aranami Toshimasa, Yamamura Takashi

Abstract excerpt

Recent reports have shown that IL-17-producing CD4+ T cells (Th17 cells) belong to a distinct helper T cell lineage and are critically involved in the pathogenesis of autoimmune diseases and allergies. However, the chemokine receptor profile of Th17 cells remains to be clarified. In this study, we report that human Th17 cells are identified as CCR2+CCR5- memory CD4+ T cells. Analysis of PBMC from healthy donors...

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Topics

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Share to Interleukin-17
Share to Receptors, CCR2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17548586
DOI: 10.4049/jimmunol.178.12.7525

Genes

CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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