Article
Cyclooxygenase-2 single-nucleotide polymorphisms and hepatocellular carcinoma in Egypt.
Molecular biology reports - 1 Mar 2014
Mohamed Faten Zahran, Hussein Yousry Mostafa, El-Deen Ibrahim Mohey, Sabea Marwa Sayed
Abstract excerpt
UNLABELLED: Hepatocellular carcinoma (HCC) is a worldwide neoplasm for which early diagnosis is difficult and the prognosis is usually poor. Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. Although several COX-2 inhibitors have been used in hepatoma therapy, the genetic background between COX-2 and HCC remains largely unknown. In this study, the...
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