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Article

Association between cyclooxygenase-2 gene polymorphisms and head and neck squamous cell carcinoma risk.

The Journal of craniofacial surgery - 1 Mar 2014

Niu Yuming, Yuan Hua, Shen Ming, Li Huizhang, Hu Yuanyuan, Chen Ning

Abstract excerpt

Cyclooxygenase-2 (COX-2) is an inducible enzyme that catalyzes prostaglandins through inflammatory response, which may be involved in autoimmune diseases and cancer pathogenesis. Two potentially functional genetic single-nucleotide polymorphisms (COX-2 -1195G>A and 8473T>C) were supposed to contribute to head and neck squamous cell carcinoma (HNSCC) susceptibility. The aim of this study was to determine the...

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PMID: 24469360
DOI: 10.1097/SCS.0000000000000372

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