Article
The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases.
Glycobiology - 1 May 2012
Izquierdo Luis, Mehlert Angela, Ferguson Michael A J
Abstract excerpt
We recently presented a model for site-specific protein N-glycosylation in Trypanosoma brucei whereby the TbSTT3A oligosaccharyltransferase (OST) first selectively transfers biantennary Man(5)GlcNAc(2) from the lipid-linked oligosaccharide (LLO) donor Man(5)GlcNAc(2)-PP-Dol to N-glycosylation sequons in acidic to neutral peptide sequences and TbSTT3B selectively transfers triantennary Man(9)GlcNAc(2) to any...
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