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Article

Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei.

The Journal of biological chemistry - 28 Mar 2014

Damerow Manuela, Rodrigues Joao A, Wu Di, Güther M Lucia S, Mehlert Angela, Ferguson Michael A J

Abstract excerpt

Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans. Despite the presence of the latter, no obvious homologues of known β1-4-galactosyltransferase or β1-2- or β1-6-N-acetylglucosaminyltransferase genes have been found in the parasite genome. However, we previously reported a family of putative...

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Identifiers

PMID: 24550396
DOI: 10.1074/jbc.M114.555029
PMCID: PMC3979372

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