Article
Molecular diversity of the Trypanosoma cruzi TcSMUG family of mucin genes and proteins.
The Biochemical journal - 1 Sept 2011
Urban Ivana, Santurio Lucía Boiani, Chidichimo Agustina, Yu Hai, Chen Xi, Mucci Juan, Agüero Fernán, Buscaglia Carlos A
Abstract excerpt
The surface of the protozoan Trypanosoma cruzi is covered by a dense coat of mucin-type glycoconjugates, which make a pivotal contribution to parasite protection and host immune evasion. Their importance is further underscored by the presence of >1000 mucin-like genes in the parasite genome. In the present study we demonstrate that one such group of genes, termed TcSMUG L, codes for previously unrecognized...
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