Article
Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs.
Clinical laboratory - 1 Jan 2011
Savino Maria, Seripa Davide, Gallo Antonietta P, Garrubba Maria, D'Onofrio Grazia, Bizzarro Alessandra, Paroni Giulia, Paris Francesco, Mecocci Patrizia, Masullo Carlo, Pilotto Alberto, Santini Stefano A
Abstract excerpt
BACKGROUND: Recent studies investigating the single cytochrome P450 (CYP) 2D6 allele *2A reported an association with the response to drug treatments. More genetic data can be obtained, however, by high-throughput based-technologies. Aim of this study is the high-throughput analysis of the CYP2D6...
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