Article
Single-nucleotide polymorphism-defined class I and class III major histocompatibility complex genetic subregions contribute to natural long-term nonprogression in HIV infection.
The Journal of infectious diseases - 1 Mar 2012
Guergnon J, Dalmasso C, Broet P, Meyer L, Westrop S J, Imami N, Vicenzi E, Morsica G, Tinelli M, Zanone Poma B, Goujard C, Potard V, Gotch F M, Casoli C, Cossarizza A, Macciardi F, Debré P, Delfraissy J F, Galli M, Autran B, Costagliola D, Poli G, Theodorou I, Riva A
Abstract excerpt
We performed a genome-wide association study comparing a cohort of 144 human immunodeficiency virus (HIV type 1-infected, untreated white long-term nonprogressors (LTNPs) with a cohort of 605 HIV-1-infected white seroconverters. Forty-seven single-nucleotide polymorphisms (SNPs), located from class I to class III major histocompatibility complex (MHC) subregions, show statistical association (false discovery...
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