Article
Immunogenetic basis of HIV-1 infection, transmission and disease progression.
Vaccine - 6 Jun 2008
Singh Paras, Kaur Gurvinder, Sharma Gaurav, Mehra Narinder K
Abstract excerpt
Susceptibility to HIV-1 infection and rate of disease progression to AIDS are complex traits modulated by environmental and genetic factors. Studies on large AIDS cohorts and their meta-analyses have identified numerous AIDS restriction genes that regulate HIV cell entry (particularly chemokine co-receptors and their ligands), acquired and innate immunity (major histocompatibility complex (MHC), killer...
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