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Article

Immunohistochemical localization of complement regulatory proteins in the human retina.

1 Mar 2012

Abstract excerpt

Age-related macular degeneration (AMD) is a complex disease. Genetic studies have found strong associations between AMD and variants of several complement pathway-associated genes. The regulation of the complement cascade seems to be critical in the pathogenesis of AMD. In 45 human donor eyes immunohistochemistry was performed using antibodies directed against major regulators of the complement system: complement...

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PMID: 22237713
DOI: 10.14670/hh-27.357

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