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Article

Therapeutic targeting of the complement system in age‐related macular degeneration: a review

1 Jan 2012

Abstract excerpt

The last decade has produced pivotal change in our understanding of the molecular mechanisms underlying age-related macular degeneration (AMD), a leading cause of global blindness. In this time, the complement system has featured as a unifying theme for several elements of new evidence: initially, the discovery of complement proteins within drusen and subsequently, the association between AMD and mutations in...

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PMID: 22304025
DOI: 10.1111/j.1442-9071.2011.02581.x

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