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Article

C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration

1 Jun 2011

Abstract excerpt

BACKGROUND: There is increasing evidence that inflammation and immune-mediated processes (complement activation) play an important role in age-related macular degeneration (AMD) pathogenesis. A genetic variation in the gene encoding complement factor H (CFH) and plasma levels of C-reactive protein (CRP), a systemic marker of subclinical inflammation, have consistently been shown to be associated with an increased...

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Identifiers

PMID: 21633121
DOI: 10.1136/bjo.2010.199216

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