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Article

The role of complement in AMD.

Advances in experimental medicine and biology - 1 Jan 2010

Zipfel Peter F, Lauer Nadine, Skerka Christine

Abstract excerpt

Age related macular degeneration (AMD) is a common form of blindness in the western world and genetic variations of several complement genes, including the complement regulator Factor H, the central complement component C3, Factor B, C2, and also Factor I confer a risk for the disease. However deletion of a chromosomal segment in the Factor H gene cluster on human chromosome 1, which results in the deficiency of...

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Source

Identifiers

PMID: 20711704
DOI: 10.1007/978-1-4419-5635-4_2

Genes

FHL1
CFHR1
CFHR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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