Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic characterization of very early-onset IBD due to mutations in the IL10, IL10 receptor alpha or beta gene: a survey of the Genius Working Group.

Inflammatory bowel diseases - 1 Dec 2013

Pigneur Bénédicte, Escher Johanna, Elawad Mamoun, Lima Rosa, Buderus Stephan, Kierkus Jaroslaw, Guariso Graziella, Canioni Danielle, Lambot Karen, Talbotec Cécile, Shah Neil, Begue Bernadette, Rieux-Laucat Frédéric, Goulet Olivier, Cerf-Bensussan Nadine, Neven Bénédicte, Ruemmele Frank M

Abstract excerpt

OBJECTIVE: Early-onset inflammatory bowel disease starting within the first months of life could be due to a particular genetic defect. We set up the GENetically determined ImmUne-mediated enteropathieS (GENIUS) network and collected infants with a proven defect of the IL10 axis for accurate phenotyping of disease presentation and evolution. DESIGN: Ten patients with early-onset inflammatory bowel disease with...

Topics

Join the communities discussing this publication.

Age of Onset
Colitis, Ulcerative
Crohn Disease
Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Interleukin

Source

Identifiers

PMID: 24216686
DOI: 10.1097/01.MIB.0000435439.22484.d3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic characterization of very early-onset IBD due to mutations in the IL10, IL10 receptor alpha or beta gene: a survey of the Genius Working Group.PMID 24216686Read ↗

Very early-onset inflammatory bowel disease (IBD) in infancy is a different disease entity from adult-onset IBD; one form of interleukin-10 receptor mutations.Semantic proximity Read ↗

Phenotypic Characterization of Very Early-Onset Inflammatory Bowel Disease with Interleukin-10 Signaling Deficiency: Based on a Large Cohort Study.Semantic proximity Read ↗

A Comprehensive Review of IL-10 and IL-10 Receptor Deficiencies: From Basic Science to Clinical Bedside.Semantic proximity Read ↗

The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review.Semantic proximity Read ↗

Immune Dysregulation Resulting From Impaired Interleukin-10 And The Interleukin-10 Receptor Signaling: A Systematic Review of 284 Monogenic PatientsSemantic proximity Read ↗

Clinical features of interleukin 10 receptor gene mutations in children with very early-onset inflammatory bowel disease.Semantic proximity Read ↗

Very early onset inflammatory bowel disease: Investigation of the IL-10 signaling pathway in Iranian children.Semantic proximity Read ↗

The diagnostic approach to monogenic very early onset inflammatory bowel disease.Semantic proximity Read ↗

Exploring genotype-phenotype correlations in three pediatric patients with IL10RA variants and very early-onset inflammatory bowel disease.Semantic proximity Read ↗

Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.Semantic proximity Read ↗

Matched Unrelated Donor Hematopoietic Stem Cell Transplant as Successful Curative Therapy for IL10RB Mutation-Associated Very Early Onset IBD.Semantic proximity Read ↗

Phenotype and Management of Infantile-onset Inflammatory Bowel Disease: Experience from a Tertiary Care Center in China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.