Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical outcome in IL-10- and IL-10 receptor-deficient patients with or without hematopoietic stem cell transplantation.

The Journal of allergy and clinical immunology - 1 Mar 2013

Engelhardt Karin R, Shah Neil, Faizura-Yeop Intan, Kocacik Uygun Dilara F, Frede Natalie, Muise Aleixo M, Shteyer Eyal, Filiz Serkan, Chee Ronnie, Elawad Mamoun, Hartmann Britta, Arkwright Peter D, Dvorak Christopher, Klein Christoph, Puck Jennifer M, Grimbacher Bodo, Glocker Erik-Oliver

Abstract excerpt

BACKGROUND: Inherited deficiencies of IL-10 or IL-10 receptor (IL-10R) lead to immune dysregulation with life-threatening early-onset enterocolitis. OBJECTIVES: We sought to gather clinical data of IL-10/IL-10R-deficient patients and devise guidelines for diagnosis and management, including hemat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis

Share to Hematopoietic Stem Cell Transplantation

Share to Immunologic Deficiency Syndromes

Share to Infant

Share to Infant, Newborn

Share to Interleukin-10

Source

Identifiers

PMID: 23158016
DOI: 10.1016/j.jaci.2012.09.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23158016-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical outcome in IL-10- and IL-10 receptor-deficient patients with or without hematopoietic stem cell transplantation.PMID 23158016Read ↗

Phenotypic Characterization of Very Early-Onset Inflammatory Bowel Disease with Interleukin-10 Signaling Deficiency: Based on a Large Cohort Study.Semantic proximity Read ↗

Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.Semantic proximity Read ↗

Matched Unrelated Donor Hematopoietic Stem Cell Transplant as Successful Curative Therapy for IL10RB Mutation-Associated Very Early Onset IBD.Semantic proximity Read ↗

The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review.Semantic proximity Read ↗

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.Semantic proximity Read ↗

A Comprehensive Review of IL-10 and IL-10 Receptor Deficiencies: From Basic Science to Clinical Bedside.Semantic proximity Read ↗

Immune Dysregulation Resulting From Impaired Interleukin-10 And The Interleukin-10 Receptor Signaling: A Systematic Review of 284 Monogenic PatientsSemantic proximity Read ↗

Unrelated donor hematopoietic stem cell transplantation for infantile enteropathy due to IL-10/IL-10 receptor defect.Semantic proximity Read ↗

IL-10 and IL-10 receptor defects in humans.Semantic proximity Read ↗

Phenotypic characterization of very early-onset IBD due to mutations in the IL10, IL10 receptor alpha or beta gene: a survey of the Genius Working Group.Semantic proximity Read ↗

Interleukin-10 and interleukin-10-receptor defects in inflammatory bowel disease.Semantic proximity Read ↗

Very early onset inflammatory bowel disease associated with aberrant trafficking of IL-10R1 and cure by T cell replete haploidentical bone marrow transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.