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Article

Inflamed gut mucosa: downstream of interleukin-10.

European journal of clinical investigation - 1 Jan 2012

Paul Gregor, Khare Vineeta, Gasche Christoph

Abstract excerpt

BACKGROUND: Interleukin-10 is a pleiotropic cytokine, whose main function is limitation and ultimately termination of immune responses. This is especially true for environmental interfaces such as the gastrointestinal tract. IL-10 acts as a key mediator for maintaining gut homeostasis. IL-10 knockout mice are well established as a genetic model for inflammatory bowel disease (IBD), and sequence variants in the...

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Source

Identifiers

PMID: 21631466
DOI: 10.1111/j.1365-2362.2011.02552.x

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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