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Article

The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review.

Clinical and experimental immunology - 23 Jun 2022

Sharifinejad Niusha, Zaki-Dizaji Majid, Sepahvandi Roya, Fayyaz Farimah, Dos Santos Vilela Maria Marluce, ElGhazali Gehad, Abolhassani Hassan, Ochs Hans D, Azizi Gholamreza

Abstract excerpt

Interleukin10 (IL10) and IL10 receptor (IL10R) deficiencies are monogenic inborn errors of immunity (IEI) causing early-onset inflammatory bowel diseases (IBD). In this report, we systematically reviewed articles that included related keywords using PubMed, Web of Science, and Scopus databases. The articles were screened for eligibility criteria before data extraction. We assessed 286 patients (44.5% female) with...

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PMID: 35481870
DOI: 10.1093/cei/uxac040
PMCID: PMC9226142

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