Article
Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells.
Scientific reports - 18 Jul 2017
Blischak John D, Tailleux Ludovic, Myrthil Marsha, Charlois Cécile, Bergot Emmanuel, Dinh Aurélien, Morizot Gloria, Chény Olivia, Platen Cassandre Von, Herrmann Jean-Louis, Brosch Roland, Barreiro Luis B, Gilad Yoav
Abstract excerpt
Tuberculosis (TB) is a deadly infectious disease, which kills millions of people every year. The causative pathogen, Mycobacterium tuberculosis (MTB), is estimated to have infected up to a third of the world's population; however, only approximately 10% of infected healthy individuals progress to active TB. Despite evidence for heritability, it is not currently possible to predict who may develop TB. To explore...
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