Article

History of tuberculosis disease is associated with genetic regulatory variation in Peruvians

2023-06-27

Abstract excerpt

A quarter of humanity is estimated to be latently infected with Mycobacterium tuberculosis ( Mtb ) with a 5-10% risk of developing tuberculosis (TB) disease. Variability in responses to Mtb infection could be due to host or pathogen heterogeneity. Here, we focused on host genetic variation in a Peruvian population and its associations with gene regulation in monocyte-derived macrophages and dendritic cells (DCs)....

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Literature Corpus work: 26e3b1bf-dbf2-5e84-91c8-d84a97e5f801
DOI: 10.1101/2023.06.20.23291558

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