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Article

Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition.

Archives of neurology - 1 May 2012

Head Denise, Bugg Julie M, Goate Alison M, Fagan Anne M, Mintun Mark A, Benzinger Tammie, Holtzman David M, Morris John C

Abstract excerpt

OBJECTIVE: APOE ε4 status has been associated with greater cortical amyloid deposition, whereas exercise has been associated with less in cognitively normal adults. The primary objective here was to examine whether physical exercise moderates the association between APOE genotype and amyloid deposition in cognitively normal adults. DESIGN: APOE genotyping data and answers to a questionnaire on physical exercise...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22232206
DOI: 10.1001/archneurol.2011.845
PMCID: PMC3583203

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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