Article
H-ficolin (ficolin-3) concentrations and FCN3 gene polymorphism in neonates.
Immunobiology - 1 Jul 2012
Michalski Mateusz, Szala Agnieszka, St Swierzko Anna, Lukasiewicz Jolanta, Maciejewska Anna, Kilpatrick David C, Matsushita Misao, Domzalska-Popadiuk Iwona, Borkowska-Klos Monika, Sokolowska Anna, Szczapa Jerzy, Lugowski Czeslaw, Cedzynski Maciej
Abstract excerpt
Serum H-ficolin (ficolin-3) concentrations (n=613) and FCN3 genotypes (n=529) from a large group of neonates are presented. Both pre-term deliveries and low birthweight (independently of gestational age) were significantly associated with low H-ficolin concentrations but not with heterozygosity for the FCN3 1637delC frameshift mutation. The presence of the variant allele, however, apparently influenced the...
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