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Article

-765 G→C and -1195 A→G promoter variants of the cyclooxygenase-2 gene decrease the risk for preeclampsia.

Genetic testing and molecular biomarkers - 1 May 2012

Gurdol Figen, Cakmakoglu Bedia, Dasdemir Selcuk, Isbilen Elif, Bekpinar Seldag, Isbir Turgay

Abstract excerpt

Cyclooxygenase-2 (COX-2) is the inducible isoenzyme of COX that leads to increased production of prostaglandins and thromboxane, the mediators of inflammation. Controversial data regarding COX levels or activities in the placentas of women with preeclampsia have led us to examine whether a single nucleotide polymorphism (SNP) in the COX-2 gene is associated with the onset of preeclampsia. Two polymorphisms in the...

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Identifiers

PMID: 22224631
DOI: 10.1089/gtmb.2011.0178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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