Article
Cell reprogramming: a new chemical approach to stem cell biology and tissue regeneration.
Current pharmaceutical biotechnology - 1 Feb 2011
Anastasia L, Piccoli M, Garatti A, Conforti E, Scaringi R, Bergante S, Castelvecchio S, Venerando B, Menicanti L, Tettamanti G
Abstract excerpt
Generation of pluripotent stem cells (iPSCs) from adult fibroblasts starts a "new era" in stem cell biology, as it overcomes several key issues associated with previous approaches, including the ethical concerns associated with human embryonic stem cells. However, as the genetic approach for cell reprogramming has already shown potential safety issues, a chemical approach may be a safer and easier alternative....
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