Article
A chemical genetics approach for specific differentiation of stem cells to somatic cells: a new promising therapeutical approach.
Combinatorial chemistry & high throughput screening - 1 Jan 2008
Sachinidis Agapios, Sotiriadou Isaia, Seelig Bianca, Berkessel Albrecht, Hescheler Jürgen
Abstract excerpt
Cell replacement therapy of severe degenerative diseases such as diabetes, myocardial infarction and Parkinson's disease through transplantation of somatic cells generated from embryonic stem (ES) cells is currently receiving considerable attention for the therapeutic applications. ES cells harvested from the inner cell mass (ICM) of the early embryo, can proliferate indefinitely in vitro while retaining the...
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