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Article

[NSI+] determinant has a pleiotropic phenotypic manifestation that is modulated by SUP35, SUP45, and VTS1 genes.

Current genetics - 1 Feb 2012

Nizhnikov Anton A, Magomedova Zalina M, Rubel Alexandr A, Kondrashkina Alexandra M, Inge-Vechtomov Sergey G, Galkin Alexey P

Abstract excerpt

We recently discovered the novel non-chromosomal determinant in Saccharomyces cerevisiae [NSI(+)] (nonsense suppression inducer), which causes omnipotent nonsense suppression in strains where the Sup35 N-terminal domain is deleted. [NSI(+)] possesses yeast prion features and does not correspond to previously identified yeast prion determinants. Here, we show that [NSI(+)] enhances nonsense codon read-through and...

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Source

Identifiers

PMID: 22215010
DOI: 10.1007/s00294-011-0363-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[NSI+] determinant has a pleiotropic phenotypic manifestation that is modulated by SUP35, SUP45, and VTS1 genes.PMID 22215010Read ↗

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