Article
Ssb1 chaperone is a [PSI+] prion-curing factor.
Current genetics - 1 Apr 2001
Chacinska A, Szczesniak B, Kochneva-Pervukhova N V, Kushnirov V V, Ter-Avanesyan M D, Boguta M
Abstract excerpt
Yeast SUP7' or SUP11 nonsense suppressors have no phenotypic expression in strains deficient in the isopentenylation of A37 in tRNA. Here we show that such strains spontaneously produce cells with a nonsense suppressor phenotype which is related to the cytoplasmically inherited determinant and manifests all the key features of the [PSI+] prion. A screen of a multicopy yeast genomic library for genes that...
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