Article
Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
Molecular carcinogenesis - 1 Oct 2012
Yew Poh-Yin, Mushiroda Taisei, Kiyotani Kazuma, Govindasamy Gopala Krishnan, Yap Lee-Fah, Teo Soo-Hwang, Lim Paul Vey-Hong, Govindaraju Selvaratnam, Ratnavelu Kananathan, Sam Choon-Kook, Yap Yoke-Yeow, Khoo Alan Soo-Beng, Pua Kin-Choo, Nakamura Yusuke, Ng Ching-Ching
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is a multifactorial and polygenic disease with high incidence in Asian countries. Epstein-Barr virus infection, environmental and genetic factors are believed to be involved in the tumorigenesis of NPC. The association of single nucleotide polymorphisms (SNPs) in LPLUNC1 and SPLUNC1 genes with NPC was investigated by performing a two-stage case control association study in a...
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