Article
A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma.
Chinese journal of cancer - 16 Dec 2015
Feng Fu-Tuo, Cui Qian, Liu Wen-Sheng, Guo Yun-Miao, Feng Qi-Sheng, Chen Li-Zhen, Xu Miao, Luo Bing, Li Da-Jiang, Hu Li-Fu, Middeldorp Jaap M, Ramayanti Octavia, Tao Qian, Cao Su-Mei, Jia Wei-Hua, Bei Jin-Xin, Zeng Yi-Xin
Abstract excerpt
BACKGROUND: Epstein-Barr virus (EBV) commonly infects the general population and has been associated with nasopharyngeal carcinoma (NPC), which has a high incidence in certain regions. This study aimed to address how EBV variations contribute to the risk of NPC. METHODS: Using logistic regression analysis and based on the sequence variations at EBV-encoded RPMS1, a multi-stage association study was conducted to...
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