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Article

A Genome Wide Study of Copy Number Variation Associated with Nasopharyngeal Carcinoma in Malaysian Chinese Identifies CNVs at 11q14.3 and 6p21.3 as Candidate Loci.

PloS one - 1 Jan 2016

Low Joyce Siew Yong, Chin Yoon Ming, Mushiroda Taisei, Kubo Michiaki, Govindasamy Gopala Krishnan, Pua Kin Choo, Yap Yoke Yeow, Yap Lee Fah, Subramaniam Selva Kumar, Ong Cheng Ai, Tan Tee Yong, Khoo Alan Soo Beng, Ng Ching Ching

Abstract excerpt

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a neoplasm of the epithelial lining of the nasopharynx. Despite various reports linking genomic variants to NPC predisposition, very few reports were done on copy number variations (CNV). CNV is an inherent structural variation that has been found to be involved in cancer predisposition. METHODS: A discovery cohort of Malaysian Chinese descent (NPC patients, n = 140;...

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Source

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Identifiers

PMID: 26730743
DOI: 10.1371/journal.pone.0145774
PMCID: PMC4701378

Genes

GRM5
MICA
GOLPH3
LILRA6
LILRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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