Article
Further evidence for the existence of major susceptibility of nasopharyngeal carcinoma in the region near HLA-A locus in Southern Chinese.
Journal of translational medicine - 22 Mar 2012
Zhao Manli, Cai Hongbing, Li Xin, Zheng Hang, Yang Xuexi, Fang Weiyi, Zhang Longcheng, Wei Ganguan, Li Ming, Yao Kaitai, Li Xin
Abstract excerpt
BACKGROUND: Nasopharyngeal carcinoma (NPC) is a multi-factorial malignancy closely associated with environmental factors, genetic factors and Epstein-Barr virus infection. Human leukocyte antigen (HLA) complex, specially the region near HLA-A locus, was regarded as a major candidate region bearing NPC genetic susceptibility loci in many previous studies including two recent genome-wide association (GWA) studies....
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