Article
Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
International journal of cancer - 15 Oct 2016
Chin Yoon-Ming, Tan Lu Ping, Abdul Aziz Norazlin, Mushiroda Taisei, Kubo Michiaki, Mohd Kornain Noor Kaslina, Tan Geok Wee, Khoo Alan Soo-Beng, Krishnan Gopala, Pua Kin-Choo, Yap Yoke-Yeow, Teo Soo-Hwang, Lim Paul Vey-Hong, Nakamura Yusuke, Lum Chee Lun, Ng Ching-Ching
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is an epithelial squamous cell carcinoma on the mucosal lining of the nasopharynx. The etiology of NPC remains elusive despite many reported studies. Most studies employ a single platform approach, neglecting the cumulative influence of both the genome and transcriptome toward NPC development. We aim to employ an integrated pathway approach to identify dysregulated pathways linked...
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