Article
Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients.
Journal of burn care & research : official publication of the American Burn Association - 1 Jan 2000
Orrey Danielle C, Bortsov Andrey V, Hoskins Janelle M, Shupp Jeffrey W, Jones Samuel W, Cicuto Bryan J, Hwang James, Jordan Marion H, Holmes James H, Haith Linwood R, Roane Brandon M, Diatchenko Luda, Cairns Bruce A, McLean Samuel A
Abstract excerpt
Increasing evidence suggests that stress system activation after burn injury may contribute to burn-related pain. If this is the case, then genetic variations influencing the function of important stress system components, such as the enzyme catechol-O-methyltransferase (COMT), may predict pain severity after thermal burn injury. The authors evaluated the association between COMT genotype and pain intensity in 57...
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