Article
Correlation Between the Warrior/Worrier Gene on Post Burn Pruritus and Scarring: A Prospective Cohort Study.
Annals of surgery - 1 May 2022
Oh Jamie, Fernando Amali, Muffley Lara, Honari Shari, Gibran Nicole S
Abstract excerpt
INTRODUCTION: Associations between genetic variation and clinical conditions suggest that single nucleotide polymorphisms (SNPs) might correlate with postburn outcomes. COMT modulates catecholamine metabolism, and polymorphisms within the rs4680 allele result in variable enzyme activity. Catechol-amines are known to modulate the inflammatory process and may affect scar formation. The aim of this study was to...
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