Article
Estimation of heritability from limited family data using genome-wide identity-by-descent sharing.
Genetics, selection, evolution : GSE - 8 May 2012
Ødegård Jørgen, Meuwissen Theo H E
Abstract excerpt
BACKGROUND: In classical pedigree-based analysis, additive genetic variance is estimated from between-family variation, which requires the existence of larger phenotyped and pedigreed populations involving numerous families (parents). However, estimation is often complicated by confounding of genetic and environmental family effects, with the latter typically occurring among full-sibs. For this reason, genetic...
Topics
- Algorithms
- Animals
- Computer Simulation
- Gene-Environment Interaction
- Genetic Loci
- Genetic Variation
- Genome
- Genome, Human
- Genotype
- Heredity
- Humans
- Likelihood Functions
- Models, Genetic
- Phenotype