Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of Attention Deficit-Hyperactivity Disorder

Abstract excerpt

<title>Abstract</title><p><bold>Background.</bold>Attention Deficit-Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with a prevalence around 5% in children and adolescents and 2.5% in adults. Recent reports using GWAS approaches have identified several genetic risk loci for this disorder. However, the epigenetic influence of extrinsic factors during pregnancy or the exposure to environmental factors...

Topics

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• Attention Deficit Disorder with Hyperactivity
• Attention Deficit Hyperactivity Disorder
• Birth Weight
• Child
• Core Binding Factor Alpha 2 Subunit
• DNA Methylation
• Pregnancy
• Prenatal Exposure Delayed Effects

Identifiers and source

Literature Corpus work

ac27d5ea-077b-5be8-9c11-ebf7986e1d2d

DOI

10.21203/rs.3.rs-5277021/v1