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Article

Variant allele of CHEK2 is associated with a decreased risk of esophageal cancer lymph node metastasis in a Chinese population.

Molecular biology reports - 1 May 2012

Gu Haiyong, Qiu Wanshan, Wan Ying, Ding Guowen, Tang Weifeng, Liu Chao, Shi Yijun, Chen Yijang, Chen Suocheng

Abstract excerpt

Growing evidence suggests that the checkpoint kinase 2 (CHEK2) signaling pathway occupies a central position in the signaling networks of DNA-damage signaling. Many functional and molecular epidemiological studies have evaluated the association between genetic variants of CHEK2 and various cancers. To evaluate the relationship between CHEK2 functional genetic variants and esophageal cancer risk and the risk of...

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Identifiers

PMID: 22201027
DOI: 10.1007/s11033-011-1410-1

Genes

CHEK2
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variant allele of CHEK2 is associated with a decreased risk of esophageal cancer lymph node metastasis in a Chinese population.PMID 22201027Read ↗

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