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Prognostic Significance of CHEK2 Mutation in Progression of Breast Cancer

18 Feb 2019

Abstract excerpt

Breast cancer (BC) is one of the most common cancers among women; genetic mutations reflect the development of this disease. Mutations in cell signaling factors can be the main cause of BC development. In this study, we focused on mutations in checkpoint kinase 2 (CHEK2) and their impact as a prognostic factor in the pathogenesis of BC. CHEK2 is controlled in cell signaling pathways through the influence of...

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PMID: 31220302
DOI: 10.1093/labmed/lmz009

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