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Article

Associations between mutations of the cell cycle checkpoint kinase 2 gene and gastric carcinogenesis.

Molecular medicine reports - 1 Oct 2017

Hong Yan, Shi Jun, Ge Zhijun, Wu Haorong

Abstract excerpt

Gastric cancer is the most common malignant tumor of the digestive system. The etiology of gastric cancer is complex, and susceptibility at the genetic level remains to be fully elucidated in genetic investigations. In the present study, mutations of the cell cycle checkpoint kinase 2 (CHEK2) gene and its association with gastric cancer were examined. Reverse transcription‑quantitative polymerase chain reaction...

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Identifiers

PMID: 29067458
DOI: 10.3892/mmr.2017.7080

Genes

CHEK2

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