Article
PTPN13 rs989902 and CHEK2 rs738722 are associated with esophageal cancer.
Annals of medicine - 1 Jan 2023
Tu Ruisha, Zhong Dunjing, Li Ping, Li Yongyu, Chen Zhuang, Hu Feixiang, Yuan Guihong, Chen Zhaowei, Yu Shuyong, Song Jian
Abstract excerpt
PURPOSE: Individual genetic background can play an essential role in determining the development of esophageal squamous cell carcinoma (ESCC). PTPN13 and CHEK2 play important roles in the pathogenesis of ESCC. This case-control study aimed to analyze the association between gene polymorphisms and ESCC susceptibility. METHODS: DNA was extracted from the peripheral blood of patients. The Agena MassARRAY platform...
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