Article
Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression.
Melanoma research - 1 Apr 2012
Liu Hongliang, Wei Qingyi, Gershenwald Jeffrey E, Prieto Victor G, Lee Jeffrey E, Duvic Madeleine, Grimm Elizabeth A, Wang Li-E
Abstract excerpt
Recently, we reported on the associations of seven single nucleotide polymorphisms (SNPs) in the promoter region of MMP1 gene with susceptibility to cutaneous melanoma (CM). Considering the reported correlation between MMP1 expression and melanoma progression, we hypothesized that these promoter SNPs might affect CM progression and prognosis. In this study, we examined the associations of seven SNPs with overall...
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