Article
Association of MMP8 gene variation with an increased risk of malignant melanoma.
Melanoma research - 1 Oct 2011
Dębniak Tadeusz, Jakubowska Anna, Serrano-Fernández Pablo, Kurzawski Grzegorz, Cybulski Cezary, Chauhan Saleena Rani, Laxton Ross C, Maleszka Romuald, Lubinski Jan, Ye Shu
Abstract excerpt
Matrix metalloproteinases (MMPs) are implicated in the development of cancers including malignant melanoma (MM) and breast cancer. We tested the possible association of MMP1 and MMP8 gene variation with these two types of cancer. We genotyped 300 unselected patients with MM, 300 consecutive breast cancer cases, 300 controls for melanoma, and 300 controls for breast cancer (age-matched and sex-matched healthy...
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