Article
Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.
European journal of cancer (Oxford, England : 1990) - 1 Jan 2011
Wang Li-E, Huang Yu-jing, Yin Ming, Gershenwald Jeffrey E, Prieto Victor G, Lee Jeffrey E, Duvic Madeleine, Grimm Elizabeth A, Wei Qingyi
Abstract excerpt
Matrix metallopeptidase 1 (MMP1) is one of the interstitial collagens in the extracellular matrix metalloproteinase family and involved in tumour behaviours. However, there is no report on the role of genetic variation in MMP1 in risk of cutaneous melanoma (CM). We investigated the association between genotypes and haplotypes of seven reported MMP1 promoter polymorphisms [-1607G ins/del (2G/1G), -839G>A, -755T>G,...
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